The Knee Society Research ProgramsYoung Investigator Research Grant ProgramIn pursuit of its mission of global leadership in education and research, The Knee Society is offering an annual research grant program for Young Investigators interested in furthering the research around the knee joint. Research proposals in consideration for a grant must be submitted by November 3, 2024. To learn more and to submit your proposal, click on the button below. SUBMIT HERE
The Knee Society Proudly Supports the Following Research Initiatives:A Multi-Organizational Research ProjectOral vs Intravenous Antibiotics for Treatment of a 2-Stage Exchange Periprosthetic Infection Javad Parvizi, MD, FRCS (Philadelphia, PA) This project is supported by The Knee Society, The Hip Society, AAHKS, MSIS, with matching funds from AAOS BOS Research Support Fund. 2021 Research GrantsThe Knee Society 2021 Research Grants are awarded to the following: GRANT ID#: 01-2021“Sleep Quality Following Total Knee Arthroplasty: A Randomized, Double Blind, Placebo Controlled Study Using Melatonin” Joshua C. Rozell, MD; Utkarsh Anil, MD; Thomas Christensen, BS; William Macaulay, MD Grant ID# 02-2021"Oral vs Intravenous Antibiotics for the Treatment of Periprosthetic Joint Infection" Graham S. Goh, MD; Javad Parvizi, MD, FRCS Note that indirect costs are not part of The Knee Society’s grant. The Knee Society does not allow overhead costs to be included in the budget statement. Other Active Research ProjectsThe Knee Society, in cooperation with the Mayo Clinic (Rochester, MN), is proud to support: Manipulation Under Anesthesia (MUA) to Treat Postoperative Stiffness after Total Knee Arthroplasty: A Randomized Clinical Trial Purpose: To determine the efficacy of manipulation under anesthesia (MUA), with and without perioperative NSAIDS and IV dexamethasone, in terms of postoperative range of motion and Knee Society scores (KSS) in patients experiencing stiffness following primary total knee arthroplasty (TKA). Study Design: Prospective, multicenter, randomized controlled trial (max of 10 centers) Exclusion Criteria: Allergy or contraindication to dexamethasone or celecoxib; diagnosis other than OA for the index TKA; age < 18 or > 90 years Treatment Groups:
Sample Size: The mean and standard deviation for sample size calculation were derived from a study by Yercan et al. In that study, the authors found that the mean ROM following MUA was 114° ± 16°. We hypothesized that a 10° difference in total range of motion would constitute a clinically significant difference. With a type I error rate of 5%, 108 total patients (54 per arm) are required to have 90% power to detect this difference. Accounting for a drop our rate of 20%, 65 patients per arm (130 total patients) will be recruited. Demographics/Patient Specifics: Age at Index Arthroplasty, Sex, BMI, ASA score, Charlson Index Randomization: Patients will be randomized using a computer generated (SAS PROC) block randomization schedule to ensure equivalent numbers of patients in each group over the course of the study Outcome Measurements:
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